Quick revision ↓ Medical Dictionary
Deep Learning — Module 05
Connect symptoms and examination findings to a differential, targeted investigations, initial priorities and reassessment.
Breathlessness framework
Assess onset, severity, exercise limitation, cough, sputum, pain, hemoptysis and associated cardiac or thromboembolic clues. Observe respiratory rate, effort, speech and mental state and measure oxygenation. Breathlessness can arise from lung, cardiac, hematological, metabolic or psychological causes. Anxiety may accompany serious respiratory disease and should not prematurely end evaluation. A quiet chest in a tiring patient can be more concerning than loud wheeze.
Asthma and variable obstruction
Asthma involves variable respiratory symptoms and variable expiratory airflow limitation, supported by objective testing when feasible. Triggers, nocturnal symptoms and variability help the history but do not independently confirm diagnosis. Long-term treatment should include an inhaled corticosteroid-containing strategy under current guidance, with technique, adherence and an action plan reviewed. Acute severe symptoms need assessment and escalation; a normal or rising carbon dioxide in a severely distressed attack can indicate fatigue.
COPD and persistent limitation
COPD assessment combines exposure history, symptoms and appropriately performed post-bronchodilator spirometry. Tobacco, biomass and occupational exposures are relevant. Exacerbations may involve infection but pneumonia, heart failure and pulmonary embolism are important alternatives or companions. Care includes exposure reduction, suitable inhaled treatment, rehabilitation and vaccination where appropriate. Oxygen targets and ventilatory support need individualized assessment, particularly when hypercapnic respiratory failure is possible.
Pneumonia, pleura and imaging
Fever, cough and focal findings can suggest pneumonia, but presentations vary in older or immunocompromised people. Imaging, severity assessment and microbiology are selected according to context. An effusion causes fluid in the pleural space, whereas pneumothorax contains air; both need assessment of cause and physiological impact. Interstitial disease may produce exertional breathlessness and fine crackles. A radiographic shadow requires clinical correlation rather than an automatic antibiotic label.
Respiratory failure
Hypoxemic respiratory failure concerns inadequate oxygenation; hypercapnic failure includes inadequate carbon dioxide elimination. Blood-gas interpretation and the clinical picture guide support. Supplemental oxygen can improve saturation while ventilatory failure continues, so monitor effort, consciousness and carbon dioxide when indicated. Escalation to noninvasive or invasive support depends on cause, contraindications and expertise. Repeated reassessment is essential after any change in oxygen or respiratory treatment.
High-Yield Revision
- A silent chest with exhaustion can indicate severe obstruction.
- Spirometry and context help confirm chronic airflow disease.
- Oxygenation and ventilation are different functions.
Common Exam & Concept Pitfalls
- Do not diagnose anxiety before assessing physiological threats.
- Do not use improved saturation as proof that ventilation is adequate.
Sources & Further Reading
Curriculum and reference review: 24 September 2026. These original notes teach clinical reasoning and recognition, not standalone prescribing or procedure protocols. International guidance supports the principles below; local pathways, resources and authorized supervision govern patient care. Faculty review is pending.
- PM&DC MBBS Curriculum 2024 — Medicine & Allied overview (printed page 20) and General Medicine section (from page 74)
- Acute assessment: Resuscitation Council UK: ABCDE · NICE adult sepsis recognition · Anaphylaxis guidance
- Cardiology: NICE acute coronary syndromes · Heart failure · Atrial fibrillation
- Respiratory: GINA 2026 asthma summary guide
- Gastrointestinal and renal care: NICE upper gastrointestinal bleeding · Acute kidney injury
- Endocrinology: 2024 multi-society hyperglycemic crises consensus · NICE thyroid disease
- Neurology: NICE stroke and TIA · Bacterial meningitis
- Allied care: NICE neutropenic sepsis · Rheumatoid arthritis · Self-harm assessment
- Continuity and safety: NICE delirium · Multimorbidity · WHO Medication Without Harm · WHO patient safety solutions
