Hypertension & Valvular Disease
Distinguish persistent hypertension from acute organ injury and connect murmur patterns with appropriate cardiac evaluation.
20 learning units • 100 chapter sections • 200 explained questions. Assess the patient, choose investigations and build a monitored management plan across adult medical specialties.
Distinguish persistent hypertension from acute organ injury and connect murmur patterns with appropriate cardiac evaluation.
Quick revision ↓ Medical Dictionary
Use a validated device, suitable cuff, supported arm and a rested patient. Repeat unexpected measurements and consider ambulatory or home monitoring for diagnostic confirmation when appropriate. Pain, anxiety and acute illness can elevate readings. Assess cardiovascular risk and possible organ damage, not merely the highest number. Review medicines, substances, adherence and features suggesting a secondary cause, especially in unusually young or resistant presentations.
Severely elevated pressure with acute neurological, cardiac, renal or retinal injury requires emergency assessment. Symptoms such as chest pain, acute breathlessness, confusion or focal weakness must not be dismissed as uncomplicated hypertension. The speed and target of reduction depend on the organ problem; indiscriminate rapid lowering can impair perfusion. Severe asymptomatic readings still require prompt evaluation and an organised plan, rather than automatic intravenous treatment.
Management combines individualised lifestyle measures, appropriate medicines and monitoring. Consider diabetes, kidney disease, orthostatic symptoms, frailty and pregnancy potential when choosing therapy. Explain why treatment matters when the patient feels well. Check adherence without blame and arrange follow-up measurements and relevant laboratory tests. Apparent resistance should prompt review of measurement, adherence, interactions and secondary causes before simply adding more medication.
Describe timing, site, radiation, intensity and associated pulse or heart-failure findings. An ejection systolic murmur radiating to the neck suggests aortic stenosis; a pansystolic apical murmur radiating toward the axilla suggests mitral regurgitation. These patterns guide investigation rather than establish severity alone. Echocardiography is needed to define anatomy and haemodynamic impact, particularly with symptoms or signs of significant disease.
Exertional syncope, angina or heart failure with suspected severe aortic stenosis warrants urgent specialist assessment. Fever with a new murmur, embolic signs or prosthetic material raises concern for infective endocarditis. Obtain appropriate blood cultures before antibiotics if this causes no dangerous delay, and seek specialist care. Valve disease management depends on symptoms, ventricular effects, anatomy and procedural suitability rather than murmur loudness alone.
Read the relevant guideline sections alongside these original clinical teaching cases. Local pathways, available services and individual patient factors determine care.
Reference review: 27 September 2026. Consult current local protocols for prescribing, procedures and escalation.