Research & Evidence-Based Medicine

20 learning units • 100 chapter sections • 200 explained questions. Build a question, judge the evidence and connect the answer with the person receiving care.

Original RAHBAR study material for the Year 3 learning pathway. Educational examples support supervised learning; institutional research and clinical requirements still apply. References & further reading ↓

MODULE 13 / 20

Diagnostic Accuracy & Test Interpretation

Use a two-by-two table to distinguish test characteristics from the probability a patient has disease.

Answer all 10 questions, then submit to see your score and explanations. This is a self-study exercise; results are not saved.

Question 01. With TP 16 and FN 4, what is sensitivity? A. 66.7%B. 90%C. 94.7%D. 80%

Question 02. With TN 72 and FP 8, what is specificity? A. 80%B. 66.7%C. 90%D. 20%

Question 03. With TP 16 and FP 8, what is positive predictive value? A. 80%B. 90%C. About 66.7%D. 16%

Question 04. With TN 72 and FN 4, what is negative predictive value? A. 72%B. About 94.7%C. 80%D. 90%

Question 05. Sensitivity is 0.8 and specificity 0.9. What is LR+? A. 8B. 0.8C. 0.22D. 9

Question 06. What does a likelihood ratio of 1 do to pretest odds? A. Doubles themB. Leaves them unchangedC. Makes disease certainD. Makes disease impossible

Question 07. With otherwise stable accuracy, lower disease prevalence usually does what to PPV? A. Raises it to 100%B. Leaves it necessarily identicalC. Lowers itD. Makes specificity equal prevalence

Question 08. What is partial verification bias? A. Every participant receives both tests independentlyB. Only a selected subset receives the reference standardC. The threshold is prespecifiedD. The sample has complete follow-up

Question 09. What does a ROC curve primarily illustrate? A. Treatment survival over timeB. A trial’s allocation sequenceC. The exact benefit of screening on mortalityD. Sensitivity and false-positive-rate trade-offs across thresholds

Question 10. Pretest probability is 20% and LR+ is 8. What is the approximate post-test probability? A. 160%B. 28%C. 66.7%D. 8%

0 / 10 answered

References & Further Reading

Use the full methods and relevant chapters when appraising a paper. These sources support further study; the examples and questions above are original teaching exercises.

Reference review: 25 September 2026. Consult current institutional guidance for project approval and clinical decisions.