Pharmacology Practice

20 learning units • 10 questions per unit • 200 explained questions

Module 19 — Cancer Therapy & Immunopharmacology

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Question 01 • Single best answer

Why do many cytotoxic drugs cause mucositis and marrow suppression?

A. All normal cells are immune to chemotherapy B. These drugs only act on bacteria C. The effects prove the tumor is cured D. Normal rapidly dividing tissues are also affected

Question 02 • Single best answer

Which protective agent is used against urotoxic metabolites in selected cyclophosphamide or ifosfamide regimens?

A. Naloxone B. Atropine C. Desmopressin D. Mesna

Question 03 • Single best answer

Which organ toxicity is particularly associated with doxorubicin?

A. Guaranteed retinal detachment B. Pure iron deficiency C. Cardiotoxicity D. Universal severe hypoglycemia

Question 04 • Single best answer

Which enzyme is inhibited by methotrexate?

A. Acetylcholinesterase B. HMG-CoA reductase C. Dihydrofolate reductase D. Gastric H-K ATPase

Question 05 • Single best answer

What determines suitability for trastuzumab in a tumor?

A. Tablet color preference B. Relevant HER2 expression or amplification C. Blood group alone D. Presence of any solid tumor

Question 06 • Single best answer

Why can checkpoint inhibitors cause inflammatory organ toxicity?

A. They directly replace cortisol in every patient B. They eliminate all T cells C. They only change urine color D. They release inhibitory constraints on immune activity

Question 07 • Single best answer

Which mechanism is shared by ciclosporin and tacrolimus?

A. Direct factor Xa inhibition B. Gastric acid neutralization C. Calcineurin inhibition with reduced T-cell activation D. Dopamine replacement

Question 08 • Single best answer

Why is infection screening important before TNF inhibitor therapy?

A. Suppressing TNF can permit reactivation of latent infection B. TNF inhibitors sterilize every organ C. Infection risk is always zero D. Screening determines tablet taste

Question 09 • Single best answer

Which intervention provides passive immunity?

A. Administration of specific immunoglobulin B. A vaccine that induces host memory C. Natural production of antibodies after infection D. T-cell priming by a vaccine

Question 10 • Single best answer

Which statement about probiotics is most appropriate?

A. Every product cures immunodeficiency B. Effects depend on strain, indication and host factors C. All strains are interchangeable D. They replace every vaccine