Pharmacology Practice

20 learning units • 10 questions per unit • 200 explained questions

Module 12 — Gastrointestinal Pharmacology

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Question 01 • Single best answer

What is the target of proton-pump inhibitors?

A. Platelet P2Y12 B. Renal ENaC exclusively C. Gastric H-K ATPase D. Dopamine transporter

Question 02 • Single best answer

How do antacids principally reduce acidity?

A. Eradication of every gastric bacterium B. Irreversible vagal destruction C. Stimulation of acid pumps D. Chemical neutralization

Question 03 • Single best answer

Which antiemetic blocks 5-HT3 receptors?

A. Metoclopramide B. Atropine C. Ondansetron D. Omeprazole

Question 04 • Single best answer

Which adverse effect is linked to metoclopramide's dopamine blockade?

A. Increased urate excretion B. Irreversible platelet inhibition C. Direct beta-2 bronchodilation D. Acute dystonia

Question 05 • Single best answer

Why should a prokinetic be avoided in suspected mechanical bowel obstruction?

A. It always cures the obstruction instantly B. It becomes an anticoagulant C. It lowers all serum electrolytes to zero D. Increased contraction does not remove the blockage and may worsen harm

Question 06 • Single best answer

Which mechanism allows oral rehydration solution to work during many diarrheal illnesses?

A. Complete inhibition of all gut absorption B. Preserved sodium-glucose cotransport C. Direct opioid receptor blockade D. Destruction of every pathogen

Question 07 • Single best answer

What does loperamide primarily do?

A. Replaces lost fluid and electrolytes directly B. Reduces intestinal propulsive motility C. Inhibits the gastric proton pump D. Provides iron replacement

Question 08 • Single best answer

Which agent is an osmotic laxative?

A. Omeprazole B. Ondansetron C. Polyethylene glycol D. Clopidogrel

Question 09 • Single best answer

What is an additional clinical use of lactulose beyond constipation?

A. Directly reversing opioid respiratory depression B. Correcting B12 deficiency C. Reducing ammonia absorption in hepatic encephalopathy D. Dissolving coronary thrombi

Question 10 • Single best answer

Why are systemic corticosteroids unsuitable for routine long-term inflammatory bowel disease maintenance?

A. Absence of any anti-inflammatory effect B. Permanent elimination of all infection risk C. Cumulative systemic toxicity D. Guaranteed cure after one dose