Pharmacology Assessment

20 learning units • 10 questions per unit • 200 explained questions

Module 08 — Cardiovascular Pharmacology

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Question 01 • Single best answer

Which mechanism helps explain ACE inhibitor cough?

A. Increased histamine H2 blockade B. Direct nicotinic stimulation C. Reduced platelet count in every patient D. Reduced bradykinin breakdown

Question 02 • Single best answer

Which laboratory change can occur with both ACE inhibitors and ARBs?

A. Obligatory severe hypocalcemia B. Hyperkalemia C. Universal neutropenia D. Reduced glucose to zero

Question 03 • Single best answer

Which calcium-channel blocker substantially suppresses AV nodal conduction?

A. Amlodipine B. Nifedipine C. Felodipine D. Verapamil

Question 04 • Single best answer

What is a major antianginal effect of venodilation by nitrates?

A. Increased platelet production B. Reduced preload and ventricular wall stress C. Increased gastric acid secretion D. Increased red-cell mass immediately

Question 05 • Single best answer

Which combination risks profound hypotension?

A. Statin plus topical emollient B. Iron plus folate when indicated C. Nitrate plus a PDE-5 inhibitor D. Insulin plus glucose monitoring

Question 06 • Single best answer

Which heart failure medicine primarily relieves fluid congestion?

A. Oral iron in a nondeficient person B. Paracetamol C. Loratadine D. Furosemide

Question 07 • Single best answer

What is digoxin's direct molecular target?

A. HMG-CoA reductase B. Gastric proton pump C. Sodium-potassium ATPase D. Beta-2 receptor

Question 08 • Single best answer

Which electrolyte abnormality increases susceptibility to digoxin toxicity?

A. Hypokalemia B. Isolated mild hypernatremia in every case C. High serum folate D. Increased HDL cholesterol

Question 09 • Single best answer

Which ECG change is associated with risk of torsades de pointes?

A. Isolated normal PR interval B. Normal sinus rhythm alone C. Prolonged QT interval D. A normal QRS axis alone

Question 10 • Single best answer

How do statins lower LDL cholesterol?

A. Inhibit HMG-CoA reductase and increase hepatic LDL clearance B. Directly lyse circulating thrombi C. Block all intestinal protein absorption D. Stimulate gastric H2 receptors

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