Pharmacology Assessment

20 learning units • 10 questions per unit • 200 explained questions

Module 15 — CNS Drugs, Epilepsy & Anesthesia

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Question 01 • Single best answer

How do benzodiazepines modify GABA-A signaling?

A. Directly block all GABA receptors B. Inhibit bacterial protein synthesis C. Irreversibly destroy sodium channels D. Increase chloride-channel opening frequency in the presence of GABA

Question 02 • Single best answer

What is the principal target of local anesthetics?

A. Platelet P2Y12 receptors B. Gastric H2 receptors C. Vitamin K epoxide reductase D. Voltage-gated sodium channels

Question 03 • Single best answer

Which drug is especially associated with T-type calcium-channel inhibition in absence seizures?

A. Ethosuximide B. Furosemide C. Clopidogrel D. Atropine

Question 04 • Single best answer

Which antiseizure drug binds synaptic vesicle protein SV2A?

A. Omeprazole B. Levetiracetam C. Warfarin D. Propranolol

Question 05 • Single best answer

Which effect can arise from dopamine D2 blockade by an antipsychotic?

A. Extrapyramidal symptoms B. Universal increased fertility C. Immediate reversal of all movement disorders D. Direct thrombolysis

Question 06 • Single best answer

Why may an SSRI show an early molecular action but delayed mood benefit?

A. The drug is never absorbed until week six B. It becomes an antibiotic first C. Clinical improvement involves downstream adaptation over time D. All serotonin receptors disappear immediately

Question 07 • Single best answer

Which change can increase lithium toxicity risk?

A. Improving documentation alone B. Applying a plain emollient C. Adding a thiazide diuretic D. Changing tablet packaging color

Question 08 • Single best answer

Why is carbidopa given with levodopa?

A. Blocks all brain dopamine receptors B. Prevents any levodopa from reaching the brain C. Reduces peripheral levodopa conversion to dopamine D. Acts as an opioid antidote

Question 09 • Single best answer

Which combination particularly raises concern for serotonin toxicity?

A. Iron with indicated folate B. A plain emollient with saline C. Calcium with vitamin D when indicated D. An SSRI with an MAO inhibitor

Question 10 • Single best answer

Why can flumazenil be hazardous in a benzodiazepine-dependent patient or mixed overdose?

A. It can precipitate seizures B. It invariably causes iron overload C. It directly dissolves fibrin D. It permanently blocks insulin

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