Pharmacology Assessment

20 learning units • 10 questions per unit • 200 explained questions

Module 07 — Autacoids, Pain, Inflammation & Gout

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Question 01 • Single best answer

Which histamine receptor mainly mediates gastric acid secretion?

A. H1 B. Nicotinic Nm C. H2 D. Beta-1

Question 02 • Single best answer

Why do many first-generation H1 antihistamines cause sedation?

A. They permanently destroy motor neurons B. They increase oxygen delivery C. They enter the CNS and block central H1 signaling D. They exclusively act on gastric H2 receptors

Question 03 • Single best answer

Which mechanism explains much NSAID-associated renal risk?

A. Reduced renal prostaglandin synthesis B. Direct insulin receptor activation C. Increased folate synthesis D. Muscarinic receptor agonism

Question 04 • Single best answer

What distinguishes aspirin's platelet effect from that of most other NSAIDs?

A. Irreversible cyclooxygenase inhibition B. Direct thrombin activation C. Reversible H1 blockade D. Increased vitamin K recycling

Question 05 • Single best answer

Which statement best describes paracetamol?

A. A potent uricosuric B. A direct thrombin inhibitor C. A muscarinic antagonist D. Analgesic and antipyretic with little peripheral anti-inflammatory action

Question 06 • Single best answer

Which opioid effect is most immediately dangerous in overdose?

A. Increased intestinal motility B. Increased lacrimation alone C. Respiratory depression D. Mild pupil constriction alone

Question 07 • Single best answer

Why can respiratory depression recur after naloxone?

A. Naloxone permanently increases opioid synthesis B. Naloxone may wear off before the opioid C. Naloxone always causes liver failure D. All opioids are eliminated within seconds

Question 08 • Single best answer

Which target is inhibited by allopurinol?

A. Acetylcholinesterase B. Gastric proton pump C. H1 receptor D. Xanthine oxidase

Question 09 • Single best answer

Which treatment goal distinguishes methotrexate from an NSAID in rheumatoid arthritis?

A. Modification of disease progression B. Immediate mechanical joint replacement C. Elimination of all monitoring D. Pure fever reduction only

Question 10 • Single best answer

Which receptor family mediates the action of triptans?

A. H2 B. Beta-2 C. 5-HT1B/1D D. Nicotinic Nm

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